Reimagining biodefense at the intersection of AI, biology and urgency.
Updated
November 5, 2025 3:05 PM

Through computational tools, Valthos analyzes biological data to design adaptive solutions against emerging threats. PHOTO: VALTHOS
Valthos has raised US$30 million in seed funding, led by the OpenAI Startup Fund, Lux Capital and Founders Fund, to advance its mission of building next-generation biodefense systems.
The company’s work comes at a time when biotechnology is evolving at an unprecedented pace. Biotechnology is moving at record speed. These new tools can lead to life-changing medical discoveries, but they also bring the risk of dangerous biological agents being developed faster than ever.
“The issue at the core of biodefense is asymmetry”, said Kathleen McMahon, co-founder of Valthos. “It’s easier to make a pathogen than a cure. We’re building tools to help experts at the frontlines of biodefense move as fast as the threats they face”. The gap Valthos aims to close is between the rapid rise of biological threats and the slower pace of developing cures. Therefore, the company is developing AI systems that can rapidly analyze biological sequences and significantly shorten the time needed to design medical countermeasures.
“In this new world, the only way forward is to be faster. So we set out to build a new tech stack for biodefense”, said Tess van Stekelenburg, co-founder of Valthos. “This software infrastructure strengthens biodefense today and lays the groundwork for the adaptive, precision therapeutics of tomorrow”.
The company was founded by van Stekelenburg, a partner at Lux Capital and McMahon, the former head of Palantir’s Life Sciences division. Together, they’ve built a multidisciplinary team of experts from Palantir, DeepMind, Stanford’s Arc Institute and MIT’s Broad Institute, bringing together deep experience in software engineering, machine learning and biotechnology.
“Technology is moving fast. An industrial ecosystem of builders, companies and solutions further democratizes AI to provide broad resilience, and ensures the U.S. continues to lead as AI increasingly powers everything around us. As AI and biotech rapidly advance, biodefense is one of the new industry verticals that helps maximize the benefits and minimize the risks”, said Jason Kwon, OpenAI’s Chief Strategy Officer. “Valthos is pushing the frontier of protection and defense in one of the most strategic intersections of multiple world-changing technologies, and with the team to do it”.
Looking ahead, Valthos plans to expand its engineering team and scale its software infrastructure for both government and commercial partners — moving closer to its goal of enabling faster, smarter and more adaptive biodefense capabilities.
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How the high-profile trial of the music mogul offers lessons for entrepreneurs on accountability, ethics, and leadership.
Updated
November 13, 2025 4:05 PM

Sean "DIddy" Combs. PHOTO: NPC NEWS
Sean “Diddy” Combs—hip-hop icon, entrepreneur, and cultural force—has built a career on his larger-than-life persona, business acumen, and ability to dominate industries ranging from music to fashion to spirits. But his recent trial, which involves explosive allegations of racketeering, sex trafficking, and transportation to engage in prostitution, has cast a shadow over his legacy.
The federal trial, which began after his arrest in September 2024, has revealed shocking claims, including coercion, manipulation, and the abuse of power in both personal and professional settings. While Combs has pleaded not guilty to all charges, the case offers valuable lessons for small business owners about leadership, ethics, and the responsibility that comes with power.
Here’s what entrepreneurs can learn from the allegations and fallout surrounding Diddy’s trial.
Diddy has been accused of creating a toxic environment that involved coercion, manipulation, and abuse of power—both in his personal relationships and his professional dealings. The trial has highlighted allegations of “freak-offs,” elaborate sexual encounters with escorts that were reportedly coerced, as well as threats of financial and reputational harm to control others.
In business, leaders hold significant power over employees, partners, and collaborators. whether through coercion, intimidation, or favoritism—can lead to toxic environments and long-term damage to the organization.
The case has shown how Diddy’s alleged actions went unchecked for years, with accusations of violence, threats, and even financial control over his accusers. Testimonies from former employees and partners reveal a pattern of behavior that created a culture of fear and silence around him.
For small business owners, this is a reminder that accountability begins with leadership. If you fail to hold yourself and others accountable, you risk fostering an environment where misconduct is ignored or accepted.
A recurring theme in the trial is how Combs’ personal actions—both alleged and confirmed—have affected his professional reputation. From footage of him physically assaulting Cassie in a hotel hallway to allegations of coercion during drug-fueled parties, the courtroom revelations have tarnished his public image and cast a shadow over his brand.
For small business owners, this reinforces an important truth: your personal behavior can have far-reaching consequences for your business. Customers, employees, and partners often associate the values and reputation of a business with its leader.
The case has also highlighted the dangers of power imbalances. Testimonies from accusers like Cassie allege that Diddy used financial control—such as threatening to withhold rent payments—to coerce others into complying with his demands.
In a small business setting, power dynamics are also present, particularly between employers and employees or business owners and partners. Misusing that power, even unintentionally, can lead to resentment, distrust, and legal challenges.
The allegations against Diddy span more than a decade, with claims of abuse dating back decades. Had there been systems in place to address grievances or hold him accountable earlier, the damage to his brand—and to the individuals involved—might have been mitigated.
For small businesses, neglecting proactive measures to address workplace issues can lead to larger crises later. Waiting until problems escalate is not only costly but can also permanently harm your business’s reputation.
The Sean “Diddy” Combs trial is a cautionary tale about the consequences of unchecked power, unethical behavior, and a lack of accountability. For small business owners, it underscores the importance of leadership that prioritizes transparency, fairness, and integrity.
Running a business isn’t just about profits—it’s about creating a legacy founded on trust and respect. By learning from the mistakes and controversies of others, entrepreneurs can build companies that inspire loyalty, foster positive relationships, and stand the test of time.