Biotechnology

How a Teen-Founded Startup Is Using AI to Reinvent Pesticide Discovery

Bindwell is testing a simple idea: use AI to design smarter, more targeted pesticides built for today’s farming challenges.

Updated

November 14, 2025 10:48 PM

Researcher tending seedlings in a laboratory environment. PHOTO: FREEPIK

Bindwell, a San Francisco–based ag-tech startup using AI to design new pesticide molecules, has raised US$6 million in seed funding, co-led by General Catalyst and A Capital, with participation from SV Angel and Y Combinator founder Paul Graham. The round will help the company expand its lab in San Carlos, hire more technical talent and advance its first pesticide candidates toward validation.  

Even as pesticide use has doubled over the last 30 years, farmers still lose up to 40% of global crops to pests and disease. The core issue is resistance: pests are adapting faster than the industry can update its tools. As a result, farmers often rely on larger amounts of the same outdated chemicals, even as they deliver diminishing returns.

Meanwhile, innovation in the agrochemical sector has slowed, leaving the industry struggling to keep up with rapidly evolving pests. This is the gap Bindwell is targeting. Instead of updating old chemicals, the company uses AI to find completely new compounds designed for today’s pests and farming conditions.  

This vision is made even more striking by the people leading it. Bindwell was founded by 18-year-old Tyler Rose and 19-year-old Navvye Anand, who met at the Wolfram Summer Research Program in 2023. Both had deep ties to agriculture — Rose in China and Anand in India — witnessing up close how pest outbreaks and chemical dependence burdened farmers.  

Filling the gap in today’s pesticide pipeline, Bindwell created an AI system that can design and evaluate new molecules long before they hit the lab. It starts with Foldwell, the company’s protein-structure model, which helps map the shapes of pest proteins so scientists know where a molecule should bind. Then comes PLAPT, which can scan through every known synthesized compound in just a few hours to see which ones might actually work. For biopesticides, they use APPT, a model tuned to spot protein-to-protein interactions and shown to outperform existing tools on industry benchmarks.

Bindwell isn’t selling AI tools. Instead, the company develops the molecules itself and licenses them to major agrochemical players. Owning the full discovery process lets the team bake in safety, selectivity and environmental considerations from day one. It also allows Bindwell to plug directly into the pipelines that produce commercial pesticides — just with a fundamentally different engine powering the science.

At present, the team is now testing its first AI-generated candidates in its San Carlos lab and is in early talks with established pesticide manufacturers about potential licensing deals. For Rose and Anand, the long-term vision is simple: create pest control that works without repeating the mistakes of the last half-century. As they put it, the goal is not to escalate chemical use but to design molecules that are more precise, less harmful and resilient against resistance from the start.

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Entertainment

What the Sean ‘Diddy’ Combs Court Case Can Teach Us About Running a Business

How the high-profile trial of the music mogul offers lessons for entrepreneurs on accountability, ethics, and leadership.

Updated

November 13, 2025 4:05 PM

Sean "DIddy" Combs. PHOTO: NPC NEWS

Sean “Diddy” Combs—hip-hop icon, entrepreneur, and cultural force—has built a career on his larger-than-life persona, business acumen, and ability to dominate industries ranging from music to fashion to spirits. But his recent trial, which involves explosive allegations of racketeering, sex trafficking, and transportation to engage in prostitution, has cast a shadow over his legacy.

The federal trial, which began after his arrest in September 2024, has revealed shocking claims, including coercion, manipulation, and the abuse of power in both personal and professional settings. While Combs has pleaded not guilty to all charges, the case offers valuable lessons for small business owners about leadership, ethics, and the responsibility that comes with power.

Here’s what entrepreneurs can learn from the allegations and fallout surrounding Diddy’s trial.

1. Leadership requires ethical responsibility

Diddy has been accused of creating a toxic environment that involved coercion, manipulation, and abuse of power—both in his personal relationships and his professional dealings. The trial has highlighted allegations of “freak-offs,” elaborate sexual encounters with escorts that were reportedly coerced, as well as threats of financial and reputational harm to control others.

In business, leaders hold significant power over employees, partners, and collaborators.  whether through coercion, intimidation, or favoritism—can lead to toxic environments and long-term damage to the organization.

  • Lesson: Ethical leadership isn’t optional—it’s foundational. A business thrives when leaders create a culture of fairness, respect, and accountability.
  • What You Can Do: Establish a code of conduct for your business that applies to everyone, including yourself. Make sure workplace policies clearly define acceptable behavior and outline consequences for unethical actions.
2. Accountability starts at the top

The case has shown how Diddy’s alleged actions went unchecked for years, with accusations of violence, threats, and even financial control over his accusers. Testimonies from former employees and partners reveal a pattern of behavior that created a culture of fear and silence around him.

For small business owners, this is a reminder that accountability begins with leadership. If you fail to hold yourself and others accountable, you risk fostering an environment where misconduct is ignored or accepted.

  • Lesson: Build a culture of accountability in your organization. As a leader, you set the tone for how issues are addressed and resolved.
  • What You Can Do: Implement systems for reporting grievances anonymously, and ensure employees know they will be heard without fear of retaliation. Create a safe space where concerns can be raised and resolved transparently.
3. Your personal actions impact your business

A recurring theme in the trial is how Combs’ personal actions—both alleged and confirmed—have affected his professional reputation. From footage of him physically assaulting Cassie in a hotel hallway to allegations of coercion during drug-fueled parties, the courtroom revelations have tarnished his public image and cast a shadow over his brand.

For small business owners, this reinforces an important truth: your personal behavior can have far-reaching consequences for your business. Customers, employees, and partners often associate the values and reputation of a business with its leader.

  • Lesson: Your personal and professional lives are intertwined when you’re a leader. Protect your reputation by maintaining integrity in all areas of your life.
  • What You Can Do: Be mindful of your actions in both personal and professional settings. If mistakes happen, address them openly and take responsibility. Transparency and integrity can help rebuild trust.
4. Power dynamics must be managed carefully

The case has also highlighted the dangers of power imbalances. Testimonies from accusers like Cassie allege that Diddy used financial control—such as threatening to withhold rent payments—to coerce others into complying with his demands.

In a small business setting, power dynamics are also present, particularly between employers and employees or business owners and partners. Misusing that power, even unintentionally, can lead to resentment, distrust, and legal challenges.

  • Lesson: Power should never be used to manipulate or control others. Instead, use your position to empower employees and foster positive relationships.
  • What You Can Do: Regularly evaluate how decisions are made in your business. Ensure fairness in hiring, promotions, and partnerships, and avoid placing undue pressure on others to comply with your expectations.
5. Proactive measures prevent crises

The allegations against Diddy span more than a decade, with claims of abuse dating back decades. Had there been systems in place to address grievances or hold him accountable earlier, the damage to his brand—and to the individuals involved—might have been mitigated.

For small businesses, neglecting proactive measures to address workplace issues can lead to larger crises later. Waiting until problems escalate is not only costly but can also permanently harm your business’s reputation.

  • Lesson: Don’t wait for a crisis to address underlying issues. Build proactive systems to identify and resolve problems before they spiral out of control.
  • What You Can Do: Conduct regular employee feedback sessions, audits of workplace culture, and reviews of leadership behavior. Stay informed about potential risks and address them early.
Conclusion

The Sean “Diddy” Combs trial is a cautionary tale about the consequences of unchecked power, unethical behavior, and a lack of accountability. For small business owners, it underscores the importance of leadership that prioritizes transparency, fairness, and integrity.

Running a business isn’t just about profits—it’s about creating a legacy founded on trust and respect. By learning from the mistakes and controversies of others, entrepreneurs can build companies that inspire loyalty, foster positive relationships, and stand the test of time.